Advanced EDTA Chelation


Clogged Arteries and Cardiovascular Health

This report discusses substances and methods used over many years to address medical problems. We wish to make it clear that the substances, methods and uses discussed in the report are not intended for use in the cure, mitigation, treatment or prevention of disease.

If you want to read this report you’re obviously worried about your heart. You may have been told that –


  • Artery blockage
  • Clogged cardiac artery
  • Total cholesterol count is too high
  • Heart surgery necessary
  • LDL is too high
  • Symptoms of Arteriosclerosis
  • Statins & other drugs prescribed etc. etc. etc.
  • Artery plaque build-up
  • Kidney Stones
  • Stent surgery required
  • HDL count is too low
  • Blood pressure is too high
  • Blood circulation is poor
  • Cardiovascular disease
  • Erectile Dysfunction
  • Drastic life style changes
  • Peripheral Artery Disease-PAD

This special research report is worth the 5 minutes of your time to read and will give you information you could use in conjunction with your physician to make decisions about your health.





According to the U.S. government, one million Americans will be killed by a clogged artery.

Every 34 seconds an American dies as the result of a blocked cardiac artery (heart attack)

There's a high percentage chance that poor circulation may trigger a serious health problem at some point in your life

More than 6.8 million Americans undergo heart bypass, balloon angioplasty and other circulation-related procedures each year

  • Every 53 seconds someone in the USA suffers a stroke
  • Heart disease is the biggest killer of both men  and women.
  • Nearly 70% of the US population has some level of heart disease.
  • Over 50% of those who have a heart attack never have a warning.  In other words, the very first symptom of heart disease for these people is a heart attack!
  • 33% of those without any prior symptoms of heart disease DIE from their first heart attack. In other words, their first symptom is death!
  • It is a silent but very deadly disease.
  • 50% of people who die of a heart attack have normal cholesterol levels.
  • 50 million suffer from high blood pressure
  • 12 million suffer from heart disease

The American Heart Association also says that some drug remedies increase the risk of a heart attack by 60%. Many high blood pressure drugs multiply the problem.



Having heart surgery is not the answer either.

Studies by Harvard Medical School  researchers and the U.S. Government's Office of Technology Assessment have concluded that a staggering 85% of bypass surgeries were not necessary.

  • Up to 42% of the 700.000 Americans who have coronary bypasses each year can expect to have diminished mental capacity.
  • Up to 50% of surgeries fail, requiring another bypass to restore adequate coronary blood flow.
  • Up to 4% die on the table.
  • 80% return to their previous condition within 7 years.
  • 19% have a heart attack, stroke or hemorrhage after surgery.
  • 30% have slight brain damage.
  • 20% suffer depression, and many men become impotent.

Unfortunately 50% of men and 63% of women who died suddenly of heart disease had NO previous symptoms





Fatty deposits called plaque starts building up at a very early age, even if you eat well and lead a healthy lifestyle, and relentlessly accumulates until the blockage leads to serious health problems.

Young arteries are flexible and supple, but early on small deposits of cholesterol and fat molecules (lipids) appear as fatty streaks.

By the time you're 30 years old, your arteries have been subjected to continuous trauma from high blood pressure events, viral and bacterial assault, and biochemical and free radical attack. As a result, the interior lining of the arteries may become more damaged, and the fatty streaks become more prolific, making the arteries less flexible.

As you approach your 40's and 50's, it is likely more damage to arterial linings has occurred and more plaque has formed. As atherosclerosis progresses, these calcified plaques multiply and blood flow is restricted. This ultimately sets the stage for the diseases that result from atherosclerosis.

Besides the arteries, calcium is also deposited in the joints, kidneys and even around the bones of the inner ear, where it can affect hearing acuity. Luckily, EDTA dissolves "metastatic" calcium — calcium deposited where it doesn't belong.




“Preventive maintenance requires a bit of a leap of faith: there's always the question, "Would I get sick if I didn't follow a preventive course or if I stopped doing so?" Do you wait until your car won't start anymore to bring it in to your mechanic, or do you bring it in every few thousand miles for a check-up? Sure, you could stop any preventive regime for a couple of years and see if something developed. But who would want to take such a high risk? The only real way to answer the question is to let the scientific literature and reason guide your decision. It is the only objective source of information we've got."


“For those who have not yet reached the symptomatic stage, preventing the onset of atherosclerotic diseases is the goal. Oral EDTA chelation retards the plaque buildup that progresses with aging, and it may even reverse plaque buildup in many cases. Think of it as an insurance policy. EDTA slows, or even reverses, to some extent, the aging of the cardiovascular system.”


"With perfect laminar blood flow a mere 19% increase in the diameter of a blood vessel will double the flow rate. In a vessel with turbulent flow, such as a diseased artery with plaque, a 10% increase in diameter will cause a doubling of blood flow"



  • Fingers or toes that often feel cold?
  • Are you experiencing loss of libido or impotence?
  • Your arms or legs often "go to sleep"?
  • Do you experience numbness in arms or legs?
  • Does your hand often cramp when writing a letter?
  • Is there a sharp, diagonal crease in your earlobe?
  • Do your lips or fingers  have a tingling sensation?
  • On short walks, do your legs get aches or pains?
  • Is your memory worse than it used to be?
  • Ankles that swell late in the day?
  • Do you get breathless on slight exertion?
  • Is there a whitish ring under the outer part of the  cornea in your eye?


“Studies by Harvard Medical School researchers and the U.S. Government's Office of Technology Assessment have concluded that a staggering 85% of bypass surgeries were not necessary. Further, The American Heart Association also says that some heart disease drug remedies increase the risk of a heart attack by 60%. Many high blood pressure drugs multiply the problem.”


“To follow the media, which features one statin commercial ad after another, one would think that cardiovascular care was all about cholesterol-lowering drugs and coronary bypass surgery. Right or wrong, these measures are important only after the disease is well established. You don’t want to let it get that far if you can help it. The trick, if you want to live a long and healthy life, is to prevent the disease from getting started in the first place-or at least, to catch it in its earliest stages, when it’s still fairly easy to treat and hasn’t done any permanent damage yet”


“Anecdotal reports have been surfacing for years of impotence, loss of libido and erectile dysfunction associated with statin drug use."

As we age, cholesterol, calcium, and other minerals accumulate on the inside lining of our blood vessels and, over time, clog them. This process is referred to variously as hardening of the arteries, atherosclerosis, arteriosclerosis, and arterial plaque buildup (see Figure 1). To ignore this process can be exceedingly dangerous and may result in rampant cardiovascular disease. Examples of such diseases are high blood pressure, angina (chest pain due to poor blood circulation to the heart), heart attack, peripheral vascular disease (poor circulation to the legs and feet), and stroke. Most of these conditions are physically disabling and depressing to the patients.

figure 1

Figure 1. The atherosclerotic process.

When plaque builds up in blood vessels, blood flow (carrying oxygen and nutrients) is restricted. It's like water flowing through a pipe clogged with mineral deposits; if the deposits are thick enough to create a complete blockage, the water will stop.

It is no different with your blood vessels. If there is excessive plaque buildup and the vessels become partially or completely blocked, not enough blood can reach the body's tissues, which become starved for the oxygen and nutrients they need. Consequently, they will not function optimally and may even die. An example is peripheral vascular disease in a diabetic, where there is insufficient blood flow to the extremities. Depending on the degree of compromise, the patient may experience pain upon walking, even short distances, or cramping in the legs or feet. Left unattended, gangrene of the feet may ensue, followed by amputation. Another example is coronary (heart) vessels that become so clogged that there is insufficient blood flow to the heart muscle itself (see Figure 2). Symptoms might be a tightness in the chest, chest pain, or discomfort in the jaw or left arm. If the blood supply is restricted for too long, a myocardial infarction, or heart attack, can occur. In this case, actual muscle tissue of the heart dies. If too much of it dies, the heart will no longer be able to pump blood to sustain life, and death will result.

Heart With Muscle Damage and a Blocked Artery

figure 2

Figure 2



It is important to recognize that hardening of the arteries is not a localized or segmental disease. It does not affect only one part of the body at a time. If your coronary arteries are clogged with plaque, it's a strong possibility that the arteries in your brain (the site of strokes), kidneys, lungs, sex organs, and other vital organs may be in a similar state.


EDTA – ethylenediamine tetra-acetic acid-may be a beneficial choice for a wide range of patients with potential markers for atherosclerosis and those with actual vessel disease. Again, results vary. It is critical to consult with a physician if you have any risk factors for cardiovascular disease. We make no claim that EDTA chelation therapy may be used to prevent, treat, cure, or mitigate atherosclerosis.

EDTA is a remarkable amino acid which, it is theorized, operates to remove the many of the heavy metals and free radicals which congest, restrict, and impede blood flow and oxygen throughout the 75,000 miles of blood vessels within the body.

It’s an amino acid, with a composition very similar to common vinegar. It was synthesized in the 1930’s, and first used in intravenous injections as a vital treatment for people who had been exposed to toxic metals levels of lead, mercury, aluminum and cadmium.

There are many years of results, and hundreds of studies, articles and reviews pointing out the potential benefits of EDTA. (See references at the end of this report)

EDTA CHELATION (pronounced “keelation”)

It is theorized that EDTA binds molecules (called chelation), such as metals or minerals and holds them tightly so they may be removed from the body. Remember results do vary.

In this way it is theorized that EDTA may clear the bloodstream of certain heavy metals by seeking them out and binding to them. The body may then flush out the EDTA, taking the metals along with it. This is theory and we cannot make the claim that EDTA will for certain remove clinically significant amounts of heavy or toxic metals from your body.

There are at least two theories for why chelation therapy is used. One is that EDTA binds to free radicals, highly active molecular fragments that can damage tissue and perhaps the lining of the blood vessels. The other is that it binds to calcium and other minerals in the bloodstream, resulting in a series of actions which may improve cellular and vascular health.

In the same way that an eggshell dissolves in vinegar EDTA may take calcium and other clogging materials off your arteries and washes the debris out through the kidneys. (Again, we make no claim that EDTA chelation therapy will prevent or treat the atherosclerotic process.)

When an individual undergoes intravenous chelation therapy, it is theorized that the EDTA makes clogged arteries and blood vessels more patent by reducing inflammation and plaque density. This therapy then may improve blood circulation, which then may lower blood pressure and possibly improve cardiovascular and vascular conditions. Clinical experience with Intravenous EDTA chelation therapy has led thousands of licensed physicians in North America to use it. Results do vary. Please note the disclaimers at the beginning and end of this article.

There are hundreds of research studies, papers and articles supporting the use of Intravenous EDTA Chelation Therapy over the past 50 years. Please see the references and studies at the end of this report.


While not understanding the full mechanism by which EDTA may work it is theorized that intravenous infusions of EDTA may gradually reduce atherosclerotic plaque and other mineral deposits throughout the cardiovascular system by literally dissolving them away. It has frequently been compared to a "Liquid Plumber” in the cardiovascular system, because it may dissolve plaque and return the arterial system to a smooth, healthy, pre-atherosclerotic state. Remember, this is a theory. EDTA is a chemical compound in which the central atom (usually a metal ion) is attached to neighboring atoms by at least two bonds in such a way as to form a ring structure. Chelating is the process in which the metal ion reacts with another molecule to form the chelate. Therein lies the potential benefit to the patient…improved vessel patency. Please note the disclaimers at the beginning and end of this Special Report.

The therapy , it is theorized, can be understood simply as the removal of calcium deposits (from your arteries, where you don't want them) and other harmful minerals that promote blood clotting and atherosclerosis. Since these harmful deposits are also known to cause excessive free radical production, EDTA chelation may also function as a powerful free radical buster — protecting cell membranes, DNA, enzyme systems, and lipoproteins from the destructive effects of these ravenous molecules. Some experts believe that the primary benefits of chelation are due to its free radical-fighting effects. 1 We can make no claim that chelation therapy will prevent, treat, cure, or mitigate the removal of calcium from your arteries, remove other harmful materials that promote blood clotting or prevent atherosclerosis.

Roto-Rooter is a better metaphor for conventional medical treatments for heart disease, all of which are closely tied to the concept of the cardiovascular system as plumbing. When a pipe/artery gets clogged, simply ream it out or flatten the deposits (angioplasty). If that doesn't work, just cut away the bad sections and replace them with a new piece of pipe (coronary artery bypass graft, or CABG). CABG, known affectionately in the medical profession as "cabbage," is the most frequently performed surgery in the United States. At $100,000 per procedure, that’s definitely a lot of "cabbage."


In the 1950's, EDTA was first used for clinical use in Michigan to treat battery factory workers who were suffering from lead poisoning.

In 1955, research conducted at providence Hospital in Detroit, Michigan, found that EDTA dissolves “metastatic calcium” i.e. calcium that has been deposited where it is not wanted, namely arteries, joints, kidneys and even the bones in the inner ear. 2,19 The first systemic study of EDTA in people with Atherosclerosis was published in 1956. 20 Twenty patients with confirmed heart disease were given a series of 30 EDTA treatments intravenously. Nineteen of the patients experienced improvement, as measured by an increase in physical activity and in another study conducted four years later, a similar group found that three months of EDTA infusions caused decreases in the severity and frequency of anginal episodes, reduced use of nitroglycerin, increased work capacity and improved Electrocardiogram results.

Since these early studies, hundreds of papers have been published on the favorable effects of chelation therapy in a variety of chronic diseases. (See references at the end of this report.)

There have been two massive meta analyses of published and unpublished studies evaluating the results of over 24,000 chelation patients. The results: 88 percent of the patients demonstrated clinical improvement. 4

One other study included 92 patients who were referred for surgical intervention. At the end of the study, only 10 required surgery either during or after their chelation therapy. 5 In another study of 2,870 patients with various degrees of degenerative diseases, especially vascular disease, almost 90% of the patients showed excellent improvement. 6 In one small, controlled crossover study of patients with peripheral vascular disease, results showed significant improvements in walking distance and ankle/brachial blood flow. 7

And when, in one study, 65 patients on the waiting list for CABG surgery (for a mean of 6 months) were treated with EDTA chelation therapy — the symptoms in 89% improved so much, they were able to cancel their surgery. In the same study, of 27 patients recommended for limb amputation due to poor peripheral circulation, EDTA chelation resulted in saving 24 limbs. 8

It soon became clear from these and later studies that EDTA treatments result in progressive and widespread improvement and stabilization of cardiovascular function. This is in contrast to standard treatments, such as angioplasty or CABG, which instantaneously restore normal function in the few treated arteries, but leave the rest of the body completely untreated (there's every reason to believe that if arteries are clogged in the heart, they're also clogged in other vital organs, like the kidneys and brain). High-tech treatments for heart disease, such as angioplasty and CABG, long hailed as medical breakthroughs, are in fact, oversold, overpriced, and ineffective, especially when compared with EDTA chelation. The truth of this assertion has been demonstrated on numerous occasions over the last 2 decades:

  • The average mortality for CABG surgery is 4% to 10%. 9,10 In fact, CABG has no overall effect on improving survival. According to one study published in the New England Journal of Medicine, "As compared with medical therapy, coronary artery bypass surgery appears neither to prolong life nor to prevent myocardial infarction in patients who have mild angina or who are asymptomatic after infarction in the five-year period after coronary angiography." 11 By contrast, mortality rates for EDTA chelation, when carried out according to accepted protocols, approaches 0%. 12
  • Grafted coronary arteries are more than 10 times as likely to close up again within 3 years compared with coronary arteries that are not replaced with a graft. 13 Improved blood flow following EDTA chelation therapy is permanent as long as regular EDTA therapy (either oral or I.V.) is maintained.
  • Significant cerebral dysfunction, especially in older patients, is commonly seen following CABG. 14 Because EDTA chelation restores blood flow to the brain, it often results in improved cognition and memory. 15
  • Atherosclerosis is typically a body-wide disease. If your coronary arteries are occluded, it's a safe bet that arteries in your brain, kidneys, lungs, and other vital organs are also occluded. Angioplasty or CABG can clean out only a few arteries supplying the heart.

Many studies that have looked at the efficacy of EDTA chelation in vascular disease have demonstrated clinical improvement. (See references at the end of this report)


Oral EDTA has been used for at least as long as its IV cousin. Intravenous EDTA chelation may have a direct and powerful effect on the body almost instantaneously. Not as convenient as swallowing a few capsules of oral EDTA per day, an IV EDTA session usually lasts about 3 hours, during which about 1000 mg to 3,000mg of EDTA (plus vitamin C and other nutrients) are administered. The number of treatments necessary (generally about 20 to 50 sessions) depends on the individual’s condition. Typical candidates for IV chelation are people who have been diagnosed with serious atherosclerosis, heavy metal poisoning, or symptoms of vascular occlusion or significant calcification of tissues. A series of needed sessions of IV EDTA will cost about $2,000 to $4,000. Oral EDTA chelation costs significantly less, about $49 a month. Again, we cannot claim EDTA Chelation Therapy will prevent, treat cure, or mitigate atherosclerosis, heavy metal poisoning, vascular occlusion, or reduce calcification of tissues.

In 1954, Dr. Harry Foreman and his colleagues performed a landmark study to determine how much orally administered EDTA the body absorbs. 16 The scientists found that the body absorbs approximately 5% of orally consumed EDTA and that it can take up to three days for the EDTA to be totally excreted. If someone consumed nutritional supplements that contained 500mg of EDTA, then we can assume from Dr. Foreman’s research that about 25mg will be absorbed each day and that 750mg will be absorbed each month. That equates to almost the same amount of EDTA administered in one intravenous chelation treatment using a low-dose optimum protocol and may affirm oral EDTA’s effectiveness over time.


When you swallow a liquid it ends up in the stomach for digestion, just like capsules. There is no “greater absorption” by liquids (otherwise every supplement would be “liquid”). In fact, the capsules will breakdown and the EDTA will be in solution in just a few minutes in your body and ready for absorption. What does not get picked up by the stomach travels the entire digestive tract. The only difference is in how the product is taken and how convenient this is for the consumer. Liquids are “messy” and there is often a bad taste but some people cannot take capsules generally because of gastric considerations and so liquids maybe a better option for them. The vast majority prefer capsules.


EDTA is used by the carload and FDA approved as a food and blood preservative. (You may have heard of it in the O J Simpson trial where it was used in Simpson’s blood sample for preservation). It is so safe it is used in baby food.

More than 200,000 children in the USA alone have been treated with EDTA for lead poisoning.

Following the guidelines of the American College of Advancement of Medicine (ACAM), estimates are at least 500,000 patients have received over 10,000,000 EDTA intravenous chelation treatments without a single fatality attributed to EDTA. This cannot be said about surgical procedures or even taking aspirin.


Erectile dysfunction may be an early warning sign of coronary artery disease, even in men without typical risk factors, new research shows. In a small study done in Italy, men with erectile dysfunction showed more signs of being on the road to coronary artery disease than men without erectile dysfunction."Erectile dysfunction should be part of a cardiovascular risk assessment. These patients should be considered at high risk for coronary artery disease and should have high priority for aggressive treatment," says Chiurlia, in a news release.

Chiurlia works for the Institute of Cardiology at Italy's University of Modena and Reggio Emilia. The study appears in the Journal of the American College of Cardiology. 17 It's "not a surprise" that erectile dysfunction and artery problems can go hand in hand, the researchers wrote. Erectile dysfunction often stems from blood vessel problems tied to atherosclerosis, the hardening of the arteries, the researchers write. They probed that connection by studying 143 men living in Italy.

All of the men were white, had similar heart health profiles, and didn't have known coronary artery disease. Seventy men were being treated for erectile dysfunction at a local clinic. Erectile dysfunction related to blood flow was verified with special Doppler testing.

In the study none of the men had coronary artery disease -- at least, not yet.

However, men with erectile dysfunction were more likely to show three early warning signs of coronary artery disease:

  • Higher levels of C-reactive protein (CRP), which is used as a marker of inflammation.
  • Abnormal blood vessel response to changes in blood flow.
  • Calcium deposits in heart arteries (coronary artery calcifications).

"We think that erectile dysfunction represents the 'tip of the iceberg' of a systemic vascular disorder, thus potentially preceding severe cardiovascular events," says Chiurlia, in the news release. (See “LOSS OF LIBIDO AND ERECTILE DYSFUNCTION”) We make no claim that EDTA chelation therapy will prevent, treat , cure, or mitigate erectile dysfunction.



by Maggie Fox, Health and Science Editor The Post Chronicle
March 16, 2010

Men with heart disease who also complain of erectile dysfunction die sooner than other male heart patients, researchers reported on Monday. They found that men who had both conditions were twice as likely to die from any cause and twice as likely to have a heart attack than men with heart disease alone. The researchers expressed concern that using drugs such as Pfizer's Viagra or Eli Lilly's Cialis to treat erectile dysfunction could mask the symptoms that point to widespread heart and artery disease and said men complaining of impotence should be checked by a cardiologist. "Erectile dysfunction is something that regularly should be addressed in the medical history of patients; it might be a symptom of early atherosclerosis," Dr. Michael Bohm of the University of Saarland in Germany, who led the study, said in a statement. His team studied 1,519 men in 13 countries taking part in some larger studies of various heart disease treatments. As part of the study the men were also asked if they had erectile dysfunction. More than half of them, 55 percent, did, Bohm's team said in a report published in the journal Circulation and also presented at a meeting of the American College of Cardiology. During the two years of the study, 11.3 percent of the patients who reported erectile dysfunction died, compared to 5.6 percent of those with mild or no impotence problems. "It has long been known that erectile dysfunction is a marker for cardiovascular disease," said Dr. Sahil Parikh at University Hospitals Case Medical Center in Cleveland, Ohio, who was not involved in the study. "In order to have proper erectile function, you have to have adequate blood flow to the genitals. If you have atherosclerosis, whether in the arteries on the neck, which can cause stroke, or the arteries of the heart, which can cause heart attack ... it is the same disease." But while the erectile dysfunction drugs help blood flow all over the body, they do not treat the underlying hardening and narrowing in the arteries that is causing the problem. "If patients have erectile dysfunction, we have to be very aggressive about screening and treating them for heart disease," Parikh said. Bohm and Parikh both agreed that patients -- and their doctors -- need to look hard at the hearts of men with erectile dysfunction.


Peripheral Artery Disease, or PAD, is caused by blockage in the arteries that slows the supply of blood to the legs. The arteries carry blood to your muscles and organs and when those arteries are clogged with plaque, it becomes difficult for blood to reach all the areas it needs to reach. PAD is not very well known among the general populace, though health professionals know it to be a painful and dangerous disease. The most common symptom of PAD is claudication, which is pain in the calves or thighs after you walk just a block or two. Usually the pain goes away after having rested for a little while. Claudication occurs because not enough blood is flowing to the muscle. During exercise, muscles needs more blood, and because of the restricted arterial blood supply associated with PAD, exercise can be painful.

PAD greatly increases the chances of heart attack or stroke. PAD usually affects older people but can affect everyone when smoking, diabetes, high blood pressure or high cholesterol are involved. PAD affects 8 to 12 million people in the United States, although most who have the disease have never heard of PAD. We can make no claim that EDTA chelation therapy will prevent, treat, cure, or mitigate PAD.


Yes you do- and some people may assume that EDTA depletes the body of needed calcium. However, when EDTA lowers blood calcium, it also stimulates the parathyroid gland to produce a hormone called parathormone. This hormone is responsible for removing calcium from places such as the inside of arteries and depositing it in the right places, such as bone.


When taken orally, EDTA, like other amino acids of similar molecular weight, passes through the stomach unaffected where it is then absorbed directly through the epithelium cells of the duodenum. Often misunderstood is the fact that stomach acidity has nothing whatsoever to do with the digestion of proteins, which all takes place via enzymatic reaction later in the duodenum, and that orally consumed Free Form Amino Acids are likewise not affected.

All Free Form Amino Acids, including EDTA, need no digestive process to enter the bloodstream. They are already small enough molecules to enter the bloodstream immediately; and that's why they are used so effectively in IV parenteral solutions. Thus all Free Form Amino Acids, including EDTA, will pass unharmed and unchanged into the duodenum where they then are directly assimilated into the bloodstream. Again, they are not, as mistakenly alleged by some, broken down or destroyed by the gastric processes.

STENTS- Does EDTA effect metal in stents and joint replacements?

EDTA has no effect on intact metals used for implants in the body, or anywhere else for that matter. EDTA binds only dissolved and positively charged (oxidized) metal ions dissolved in solution. Stents and joint replacement are made from alloys such as highly refined stainless steel, vanadium alloys aned titanium, that will not dissolve in body fluids.


It's always important to supplement your diet with a good mineral supplement because: 1) physical or emotional stress causes a drain on the body's resource of minerals, and a mineral deficiency can result in illness. 2) According to the 1992 Earth Summit Report, America's soil has suffered an 85% mineral depletion in the last 100 years, which means we're only getting a fraction of the minerals we need from our food.


This is a Foreword to “A Textbook on EDTA Chelation Therapy” edited by Elmer M. Cranton, MD.

Linus Pauling

Linus Pauling, PhD is the only person ever to have received two full, unshared Nobel Prizes. He was one of the world's greatest biochemists and scientists. Before his death he wrote and researched extensively in the field of alternative and nutritional medicine.




by Linus Pauling, PhD

For more than twenty years I have devoted most of my time to research and education in the fields of nutrition and preventive medicine. I have written and lectured extensively about simple, safe and inexpensive measures to improve the length and quality of life. In my recent book, “How to Live Longer and Feel Better”, I covered that subject at length. EDTA chelation therapy fits in well with my views on health care.

EDTA is not normally present in the human body and is therefore, by definition, not an orthomolecular substance. Chelation, however, is far safer and much less expensive than surgical treatments for atherosclerosis. Physicians who adhere to the protocol for safe and effective administration of EDTA, as approved and promulgated by the American College of Advancement in Medicine, integrate the results of my own research into their chelation program. That protocol is published in its entirety in this book. Improved nutrition and supplementation with vitamins and trace elements is an important part of the overall chelation program.

EDTA chelation therapy makes good sense to me as a chemist and medical researcher. It has a rational scientific basis, and the evidence for clinical benefit seems to be quite strong. Metallic ions play an important role in the formation of atherosclerotic plaque. EDTA removes those ions with relative safety and without surgery. Published research and extensive clinical experience show that EDTA helps to reduce and prevent atherosclerotic plaques, thus improving blood flow to the heart and other organs. The scientific evidence indicates that a course of EDTA chelation therapy might eliminate the need for bypass surgery. Chelation has an equally valid rationale for use as a preventive treatment.

Past harassment of chelating physicians by government agencies and conservative medical societies seems to stem largely from ignorance of the scientific literature and from professional bias.

A reference book such as this, which assembles a large body of scientific knowledge about EDTA chelation therapy into one volume, will be of great advantage to physicians who desire to learn more about this emerging nonsurgical treatment for atherosclerosis and related age-associated diseases.

Palo Alto, California July, 1988


Linus Pauling

Is a world renowned expert and is the founder of American College for Advancement in Medicine which has over 1,000 MD members who deliver intravenous therapy. Dr Gordon is a long-time advocate of the effectiveness of Oral EDTA and of its use as an adjunctive to intravenous EDTA.

Dr Gordon’s preferred oral formula combines garlic together with the EDTA.



Because kidney stones are usually composed of calcium and oxylate, and because virtually all EDTA passes through the kidneys on its way out of the body, it is theorized that EDTA is capable of helping remove them


Dr. Gordon’s use of garlic is based on available research. “Atherosclerosis”, a journal focusing on the major disease of arteries, recently published a randomized, double-blind, placebo-controlled study showing that garlic appears to prevent plaque buildup in arteries. In a 4-year study of 280 adults, German researchers found that subjects taking nearly one gram of garlic per day (900 mg) had up to an 82% reduction in the plaque volume in their arteries, compared to controls who took placebo, a "dummy" powder, instead. 18 It is theorized that garlic may play a role in "thinning" the blood.


Malic acid is a weak, organic acid found in apples. It is theorized to act as a chelating agent in removing the very toxic aluminum . 21


Reduced blood supply is often the culprit in sexual impotency. Improved circulation improves libido and potency and will noticeably improve sexual feelings and performance in both men and women.


EDTA is the FDA-approved treatment for lead, mercury, aluminum, and cadmium poisoning .The accrual of heavy metal toxins invites an increased risk for various diseases., especially heart disease. Theory suggests EDTA may normalize the distribution of many metallic elements in the body..


Why would anyone opt for invasive, less lasting options, such as angioplasty or CABG, when an alternative for restoring normal or near-normal circulatory functioning of the vasculature exists? It seems that IV EDTA should be an important treatment. Few, if any, would opt for surgical treatment if they were aware and informed about the value of IV EDTA chelation. However, there are organizations and institutions that see political gain in cloaking the truth about EDTA's benefits.

Each CABG might cost $100,000; each angioplasty costs about $25,000; drugs for reducing cholesterol, lowering high blood pressure, and normalizing heart rhythm bring the pharmaceutical industry billions of dollars each year. And these are only a few examples. We cannot make the claim that chelation therapy reduces cholesterol but theoretical evidence is compelling. By contrast, the cost of chelation therapy, cited above, is minimal. The patent for EDTA has long expired and the modern drug establishment is unwilling to pour in the millions of dollars required for extensive testing of a substance that they will not have exclusive rights to when they are done. You may be hearing more about chelation soon.

The National Institute of Health is currently doing a large clinical double-blind trial on EDTA chelation therapy for coronary heart disease with thousands of patients. This $30 million IV Chelation study is a ten year study and is scheduled to run through 2013. This is an acknowledgement of the seriousness which the medical establishment now takes EDTA Chelation therapy..

The lack of acceptance by mainstream medicine should not prevent those interested in its claims from examining the objective evidence.


That's a simple and important question with a complex answer. Much depends on why you're taking it and how sick you are. If you have serious or advanced cardiovascular disease with major occlusions, there are various objective measures your doctor can use to gauge your progress. These include tests for blood lipid, homocysteine, lipoprotein a, and fibrinogen levels, platelet aggregation tests, various functional tests (treadmill, Master's two-step, etc.), and non-invasive doppler tests of blood flow. If EDTA is doing what it should, these tests should indicate objective improvements.

Just as important, you may start feeling better as blood starts to reach areas of your body in greater volume than it has in years. Improved circulation has been shown to result in such changes as better memory function, reversal of diabetic gangrene, decreased macular degeneration and improved vision in people with diabetic neuropathy, reduced intermittent claudication, and improved heart function.

Such improvements are bound to make you feel better, more energetic, and more alert. If you have any doubt, try testing your mental function objectively using ThinkfastPRO.

Preventive maintenance requires a bit of a leap of faith: there's always the question, "Would I get sick if I didn't follow a preventive course or if I stopped doing so?" Do you wait until your car won't start anymore to bring it in to your mechanic, or do you bring it in every few thousand miles for a check-up? Sure, you could stop any preventive regime for a couple of years and see if something developed. But who would want to take such a high risk? The only real way to answer the question is to let the scientific literature and reason guide your decision. It is the only objective source of information we've got.



If you’re reading this report you’re obviously worried about your heart and what will you be prescribed?

Lipitor, Lescol, Mevacor, Pravachol, Zocor, Crestor, (a seventh statin, Baycol was removed from the market during the summer of 2001 because of potentially serious side effects.)

(The obvious improvements to your health like eating right, exercising, losing weight, less salt, less sugar etc.- we won’t deal with all those here—you’ve heard them before and you know what you can do, how to do it and if you want to do it!)

This may be the first time you have seriously rubbed shoulders with the Drug Industry. Your Doctors want you to take powerful Statin prescription drugs to reduce your cholesterol and various other—probably at the same time- drugs to reduce your blood pressure.

Your Doctor may have told you that if he/she had his way he would prescribe these drugs for everybody in the world since they are so good at achieving reductions in cholesterol count or blood pressure. When I hear this I get nervous. The same people doing all the studies are now telling you we all need to take powerful drugs with significant side effects for the rest of our lives! What they don’t tell you is what this all has to do with eliminating Cardiovascular Disease!

We’re not going to inundate you with 500 pages on the efficacy of Statins and Blood pressure lowering drugs (Click here to if you want to read more on Statins), but we will take the other side and give you some data and places to look to form your own opinion amongst the bewildering array of experts and pseudo experts.

We are worried about the side effects. You may have heard about the usual ones, cast aside as “rare”-“Side effects occur infrequently and include muscle aches, constipation, weakness, abdominal pain, and nausea.” etc.etc. Believe me they’re not so rare.

What they don’t tell you are the other ones where the brain’s normal memory functions are impaired.


Jim Matthews (CBS TV News)
O’Fallon, Ill., May 24, 2004


Some doctors are so high on statins, they seem to think most everyone should take them, that there's no down side. Lipitor's maker even says it may help Alzheimer's patients.

(CBS) When Jim Matthews needed to slash his cholesterol and heart attack risk, he joined the millions taking the world's top-selling drug, Lipitor.

After five weeks, he was struck by cognitive chaos and confusion.

All of a sudden, he found himself asking: "Did I go get the mail or did I just think I was going to go get the mail? Did I give my dog her thyroid pill, or did I just think I gave the dog the thyroid pill?"

He couldn't function for hours.

When he came back to his senses, he suspected Lipitor was to blame, but only found one glowing report after another on Lipitor and similar drugs - all called statins.

In fact, some doctors are so high on statins, they seem to think most everyone should take them, that there's no down side. Lipitor's maker even says it may help Alzheimer's patients.

But researcher Dr. Beatrice Golomb warns the studies generating the bulk of the positive press were funded by the companies that make the drugs, like Pfizer, which earns $9 billion a year from Lipitor.

"I made the decision that I really didn't want to take money from the drug industry," says Golomb.

Funded by the government and not the drug makers, Golomb is taking an independent look at studies already done on statins, pinpointing severe muscle problems, which Pfizer has disclosed, and cognitive dysfunction -- not mentioned in patient leaflets.

"We have people who have lost thinking ability so rapidly that within the course of a couple of months they went from being head of major divisions of companies to not being able to balance a checkbook and being fired from their company," says Golomb, an assistant professor or medicine at the University of California in San Diego.

Golomb says statins do help the heart, but may also hamper the brain's performance and trigger other serious problems. She's leading an independent clinical trial to find out what harm statins may be doing. The results should be out in a few months.

Pfizer told us Lipitor's safety is supported by peer reviewed articles and scores of studies,"including the most extensive statin clinical trial program ever conducted." Pfizer "collects all available safety information...and shares (it) with regulatory authorities worldwide."

That may be right for most patients, but Matthews isn't looking for a repeat of his mental meltdown. He's taking a new tactic: trying to tame his cholesterol with diet and exercise

"Up with the good cholesterol, down with the bad," he says.


The myopathies (muscle aches and pains) associated with the use of statins may be related to their ability to block not only the body's cholesterol production but also its production of coenzyme Q10 (Co Q10). This is a vitamin like substance found in all human cells that's critical for the production of energy; in fact, 95 percent of all the energy made by our cells is produced with the assistance of Co Q10. Organs that need the most energy — such as the heart, lungs, and liver — have the highest CoQ10 concentrations. Why is this so important? Because studies dating as far back as 1993 have shown that statins can reduce blood levels of Co Q10 by up to 40 percent! The consequences are unclear, but some researchers are looking at the role of Co Q10 in congestive heart failure and other medical conditions.




What... nobody mentioned that to you?
Maybe they thought you were past that “phase” in your life and it wasn’t going to bother you.


Former USAF Flight Surgeon
Former NASA Astronaut
Retired Family Doctor

“Anecdotal reports have been surfacing for years of impotence, loss of libido and erectile dysfunction associated with statin drug use. I have summarized the available review articles, called attention to the most relevant of anecdotal case reports, reviewed relevant research studies and included a list of most relevant references in the preparation of this paper.

The findings of Kash Rizvi et al in their 2002 review of erectile dysfunction leave little doubt that a strong relationship exists between the taking of statin drugs and erectile dysfunction.

Applying the criteria suggested by Sackett and colleagues in their book, “Clinical Epidemiology: A Basic Science for Clinical Medicine” most would say that the strength of the relationship is sufficiently strong that it should be called “probably causal”.

In a review of France and Spain’s adverse drug reports by Bagheri and others, 74 cases of impotence associated with statin drug use were reported. In 85% of these cases the condition regressed completely when the statin drug was stopped.

Bruckert et al concluded that erectile dysfunction is a frequent disorder in hyperlipidemic men treated with statins. Their study group consisted of 339 age-matched men 40-50 years of age. If these otherwise healthy men were on either a statin drug or a fibrate derivative, impotence was much more likely.

L. de Graff and colleagues reported that decreased libido is a probable adverse drug reaction of statin drugs and is generally reversible. They added that this reaction may be caused by low serum testosterone levels, mainly due to cholesterol depletion.

Jackson reported on five men with coronary artery disease who developed impotence within oneweek of starting treatment with simvastatin 10 mg or having the dose increased to 20 mg.

All investigators in this field stress the likelihood of gross under-reporting of impotence, erectile dysfunction and loss of libido in the usual doctor / patient interaction.

If the examining physician does not specifically ask the question as to sexuality problems, it is very unlikely to be brought up by the patient. When studied as a separate issue, however, the preceding reports well document the importance of impotence, loss of libido and erectile dysfunction as a statin drug side effect.

Although some postulate a CNS explanation for the effect of statins on sexuality, diminished testosterone production due to relative depletion by statins of its cholesterol precursor deserves serious consideration as a causative factor.

The following link will help you understand the current thinking on Statins and Cholesterol: Click here


The information in this report is definitely not intended to be a substitute for careful medical evaluation and treatment by a competent and licensed health care professional. We strongly recommend that you do not change any current medications or add any new therapies without personally consulting a fully qualified and licensed health care professional.

Varying and even conflicting views are held by other segments of the medical profession. The information presented on this website is intended to be educational in nature and is not intended as a basis for diagnosis or treatment. It is expected, however, that information here will be contradicted from time to time by various other medical authorities and researchers in support of their own agendas. This website is published and distributed for educational purposes.




These statements have not been evaluated by the FDA. We make no claims that Advanced Formula EDTA Oral Chelation Capsules will unclog your arteries and/or restore cardiovascular function, lower cholesterol levels, reduce blood pressure, prevent heart attacks or strokes, reduce symptoms of patients suffering from coronary artery disease or angina, prevent atherosclerosis, erectile dysfunction, PAD, or eliminate kidney stones.


You have nothing to lose with our
unconditional guarantee (see below)



You have NOTHING TO LOSE—there is an unconditional guarantee if you fail to feel the difference in your well-being and see tangible results after using ADVANCED FORMULA EDTA ORAL CHELATION. Return the unused portion for a full refund, NO QUESTIONS ASKED!

Advanced Formula EDTA Oral Chelation is the only product we manufacture. It’s what we know and it’s too important to be mixed in with a variety of other dietary supplements, diluting our focus. It’s manufactured at an FDA approved facility in the USA.

We developed our ADVANCED FORMULA EDTA oral chelation product with reference to all the available science developed over the past 50 year and with special reference to Dr Garry Gordon’s preferred protocol of combining Garlic and EDTA in an easy to take capsule..



In order to check the effectiveness of any cholesterol management program we recommend that you purchase a home cholesterol test from your local drug store or on the internet.(About $10 each test) Before you begin a program take your total cholesterol measurement. After 90 days check the measurement again. Check regularly thereafter. For your blood pressure management we recommend purchasing a home blood pressure unit ( with arm cuff- not wrist or any other measurement way) such as "Lumiscope" (about $50) or any other quality unit from a drug store or the internet and measure your blood pressure before beginning a program and then regularly thereafter. Once you know you are getting control of your cardio and artery health you will enjoy a new found confidence which can only accelerate your well-being.



Suggested 4 capsules daily
Contents 120 Capsules




EDTA (calcium disodium)

250 mg *

1,000 mg

Malic Acid

250 mg *

1,000 mg

Garlic (Deoderized)

100 mg *

400 mg

Parsely Powder

25 mg *

100 mg

* Daily Value not established

Other Ingredients: Rice Flour, Silica and Gelatin capsule.

EDTA is the synthetic amino acid which closely resembles four molecules of vinegar. It is never broken down in your body. It goes in and comes out as EDTA, attaching to metals and minerals, forming a bond called a chelate.

GARLIC EXTRACT it is theorized, may play a role in "thinning" the blood. also has anti-blood clotting properties.

MALIC ACID is a weak, organic acid found in apples. It is theorized to act as a chelating agent in removing aluminum.

PARSLEY is a rich source of the green plant pigment chlorophyll, which is a powerful breath freshener.



Order Advanced Formula EDTA Oral
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Made in the U.S.A.


You have NOTHING TO LOSE—there is an unconditional guarantee if you fail to feel the difference in your well-being and see tangible results after using ADVANCED FORMULA EDTA ORAL CHELATION. Return the unused portion for a full refund, NO QUESTIONS ASKED!

45 East 89th. St. New York, NY 10128



Use only as directed. Advanced Formula EDTA Oral Chelation should not be taken by anyone that currently has Liver or Kidney disorders nor by pregnant or lactating women.

Keep out of reach of children

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease.


The information provided herein is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment.

You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.


If you have advanced cardiovascular disease and are interested in intravenous (IV) chelation, you can find a chelating physician near you by contacting The American College for the Advancement in Medicine (ACAM) , 24411 Ridge Route, Suite 115, Laguna Hills, CA 92653



  1. Cranton, Elmer. Bypassing Bypass (2d Ed). Medex Publishers, Trout Dale, VA 24378-0044, 1992.
  2. EDTA Chelation: A Misunderstood Therapy for Atherosclerosis and Other Diseases, by Ward Dean, MD, August 1997, VRP Library.
  3. Harman, D. The biologic clock: The mitochondria? J Am Geriatr Soc, 1972; 20: 145-147.
  4. These papers, The correlation between EDTA Chelation Therapy and improvement in cardiovascular function: A Meta-Analysis, and EDTA Chelation Treatment for vascular disease: A Meta-Analysis using unpublished data, both by L.T. Chappell and J.P. Stahl, were published in the Journal of Advancement in Medicine in 1993 and 1994.
  5. Hancke, C. and Flytlie, K, Benefits of EDTA Chelation Therapy in Arteriosclerosis: A retrospective study of 470 patients, Journal of Advancement in Medicine, 1993; 6:3, 161-171.
  6. Olszewer E, Carter JP. EDTA chelation therapy in chronic degenerative disease. Med Hypotheses. 1988; 27:41-49. Abstract
  7. Olszewer E, Sabbag FC, Carter JP. A pilot double-blind study of sodium-magnesium EDTA in peripheral vascular disease. J Natl Med Assoc 1990; 82:173-174. Abstract
  8. Hancke C, Flytie K. Benefits of EDTA chelation therapy on arteriosclerosis. J Adv Med. 1993; 6:161-172.
  9. Edmunds LH, Stephenson LW, Edie RN, Ratcliffe MB. Open-heart surgery in octogenarians. N Engl J Med. 1988; 319:131-136.
  10. CASS Principal Investigators and the Associates. Coronary artery surgery study (CASS): a randomized trial of coronary artery bypass surgery: Survival data. Circulation. 1983; 68:939-950.
  11. CASS Principal Investigators and the Associates. Myocardial infarction and mortality in the Coronary Artery Surgery Study randomized trial. N Engl J Med. 1984; 310:750-758.
  12. Chappell LT, Janson M. EDTA chelation therapy in the treatment of vascular disease. J Cardiovasc Nurs. 1996;10:78-86.
  13. Cashin WL, Sanmarco ME, Nessim SA, Blankenhorn DH. Accelerated progression of atherosclerosis in coronary vessels with minimal lesions that are bypassed. N Engl J Med. 1984; 311:824-828.
  14. Arom KV, Cohen DE, Strobl FT. Effect of intraoperative intervention on neurological outcome based on electroencephalographic monitoring during cardiopulmonary bypass. Ann Thorac Surg. 1988; 48:476-483.
  15. Olszewer E, Carter JP. EDTA chelation therapy in chronic degenerative disease. Med Hypotheses. 1988;27:41-49. Abstract
  16. Foreman, H., Trujillo, T. The metabolism of C14 labeled ethylenediaminetetraacetic acid in human beings. J Lab Clin Med, 1954, 43: 566-571
  17. J Am Coll Cardiol, 2005; 46:1503-1506 doi:10.1016/j.jacc.2005.06.068 (Published online 27 September 2005). Abstract
  18. Koscielny J, Klussendorf D, Latza R, Schmitt R, Radtke H, Siegel G, Kiesewetter H. The antiatherosclerotic effect of Allium sativum. Atherosclerosis 1999;144:237-49.
  19. Clarke, NE, Clarke, CN, Mosher, RE (1955). The "in vivo" dissolution of metastatic calcium. An approach to atherosclerosis. Am J Med Sci 229:142.
  20. Clarke, NE, Clarke, CN, Mosher RE (1956). Treatment of angina pectoris with disodium ethylene diamine tetraacetic acid. Am J Med Sci 232:654.
  21. Llobet JM, Domingo JL, Gomez M, Tomas JM, Corbella J. Acute toxicity studies of aluminium compounds: antidotal efficacy of several chelating agents. Pharmacol Toxicol 1987 Apr;60(4):280-3.


This link will take you further to another 500 studies on Oral EDTA Chelation

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